A VETERINARY PHARMACEUTICAL COMPANY BASED IN LAGOS, NIGERIA.

amproliumAMPROLIUM® HYDROCHLORIDE

Feed Grade Anti-Coccidial Powder

Constituent

99% Pure Amprolium Hydrochloride

Properties and Description:

Amprolium Hydrochloride is a broad spectrum, potent coccidiostat (anti-protozoal) used for the treatment and prevention of Coccidiosis in cattle, goats, sheep, and poultry (chicken and turkey). Amprolium demonstrates profound activity against Eimeria spp., especially Eimeria tenella, Eimeria acervulina and Eimeria necatrix. It is a thiamine (vitamin B1) analogue and its pharmacological effect relies on the competitive inhibition of thiamine uptake, where it demonstrates its mode of action. Amprolium competitively inhibits the active transport of thiamine in isolated second-generation schizonts of Eimeria spp., and in host intestinal cells. Upon ingestion of Amprolium, the coccidia experience thiamine deficiency and starve from malnutrition. It is in form of a white-crystalline, soluble powder.

Indications:

Indicated for prevention and treatment of all forms of Coccidiosis in livestock. Combination with Sulfaquinoxaline has been shown to increase potency.

Side-Effects: Over dosage of Amprolium can suppress weight gain in broilers and cause polyneuritis. Long term administration of Amprolium in high doses may result in Thiamine (Vitamin B1) deficiency in the host. To treat Amprolium overdose, thiamine should be administered parenterally or orally.

Dosage: For Oral Administration in feed and water.

Calves: 10mg/kg of body weight

Lamb: 55mg/kg of body weight

Poultry: 0.012-0.025% in water; 120-250g/tonne of feed

Note: Not intended for hens producing eggs for human consumption. In severe cases, curative treatment may be followed by preventive treatment.

Withdrawal times: For Meat.

Calves, Goats, Sheep: 3days.

Poultry: 3days.

Warning: Keep out of the reach of children.

Presentations: 25kg, 1kg, 500g.

 

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